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Dr. Desai’s interdisciplinary research focuses on biochemical approaches to rational drug design. These approaches include biophysical spectroscopic techniques, enzyme kinetics, site-directed mutagenesis, organic synthesis, and molecular modeling. Targeted areas of drug design are: activators of antithrombin that function as anticoagulants, engineering inhibitory properties in corticosteroid binding globulin and serpin mechanism. Understanding sugar–protein and steroid–protein interactions at a molecular level guides the rational drug design.
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